Lying near the head of Southampton Water, a peninsula between the estuaries of the Rivers Test and Itchen, Southampton is Britain’s largest cruise port. It has been one of England’s major ports since the Middle Ages, when it exported wool and hides from the hinterland and imported wine from Bordeaux. The city suffered heavy damage during World War Two and as a result the centre has been extensively rebuilt, but there are still some interesting medieval buildings including the Bargate, one of the finest city gatehouses in England.

La Coruña, the largest city in Spain's Galicia region, is among the country's busiest ports. The remote Galicia area is tucked into the northwest corner of the Iberian Peninsula, surprising visitors with its green and misty countryside that is so much unlike other parts of Spain. The name "Galicia" is Celtic in origin, for it was the Celts who occupied the region around the 6th-century BC and erected fortifications. La Coruña was already considered an important port under the Romans. They were followed by an invasion of Suevians, Visigoths and, much later in 730, the Moors. It was after Galicia was incorporated into the Kingdom of Asturias that the epic saga of the Pilgrimage to Santiago (St. James) began. From the 15th century, overseas trade developed rapidly; in 1720, La Coruña was granted the privilege of trading with America - a right previously only held by Cadiz and Seville. This was the great era when adventurous men voyaged to the colonies and returned with vast riches. Today, the city's significant expansion is evident in three distinct quarters: the town centre located along the isthmus; the business and commercial centre with wide avenues and shopping streets; and the "Ensanche" to the south, occupied by warehouses and factories. Many of the buildings in the old section feature the characteristic glazed façades that have earned La Coruña the name "City of Crystal." Plaza Maria Pita, the beautiful main square, is named after the local heroine who saved the town in 1589 when she seized the English standard from the beacon and gave the alarm, warning her fellow townsmen of the English attack.

Valencia, Spain's third-largest municipality, is a proud city with a thriving nightlife and restaurant scene, quality museums, and spectacular contemporary architecture, juxtaposed with a thoroughly charming historic quarter, making it a popular destination year in year out. During the Civil War, it was the last seat of the Republican Loyalist government (1935–36), holding out against Franco’s National forces until the country fell to 40 years of dictatorship. Today it represents the essence of contemporary Spain—daring design and architecture along with experimental cuisine—but remains deeply conservative and proud of its traditions. Though it faces the Mediterranean, Valencia's history and geography have been defined most significantly by the River Turia and the fertile huerta that surrounds it.The city has been fiercely contested ever since it was founded by the Greeks. El Cid captured Valencia from the Moors in 1094 and won his strangest victory here in 1099: he died in the battle, but his corpse was strapped into his saddle and so frightened the besieging Moors that it caused their complete defeat. In 1102 his widow, Jimena, was forced to return the city to Moorish rule; Jaume I finally drove them out in 1238. Modern Valencia was best known for its frequent disastrous floods until the River Turia was diverted to the south in the late 1950s. Since then the city has been on a steady course of urban beautification. The lovely bridges that once spanned the Turia look equally graceful spanning a wandering municipal park, and the spectacularly futuristic Ciutat de les Arts i les Ciències (City of Arts and Sciences), most of it designed by Valencia-born architect Santiago Calatrava, has at last created an exciting architectural link between this river town and the Mediterranean. If you're in Valencia, an excursion to Albufera Nature Park is a worthwhile day trip.

Since being designated a European Capital of Culture for 2013, with an estimated €660 million of funding in the bargain, Marseille has been in the throes of an extraordinary transformation, with no fewer than five major new arts centers, a beautifully refurbished port, revitalized neighborhoods, and a slew of new shops and restaurants. Once the underdog, this time-burnished city is now welcoming an influx of weekend tourists who have colonized entire neighborhoods and transformed them into elegant pieds-à-terre (or should we say, mer). The second-largest city in France, Marseille is one of Europe's most vibrant destinations. Feisty and fond of broad gestures, it is also as complicated and as cosmopolitan now as it was when a band of Phoenician Greeks first sailed into the harbor that is today's Vieux Port in 600 BC. Legend has it that on that same day a local chieftain's daughter, Gyptis, needed to choose a husband, and her wandering eyes settled on the Greeks' handsome commander Protis. Her dowry brought land near the mouth of the Rhône, where the Greeks founded Massalia, the most important Continental shipping port in antiquity. The port flourished for some 500 years as a typical Greek city, enjoying the full flush of classical culture, its gods, its democratic political system, its sports and theater, and its naval prowess. Caesar changed all that, besieging the city in 49 BC and seizing most of its colonies. In 1214 Marseille was seized again, this time by Charles d'Anjou, and was later annexed to France by Henri IV in 1481, but it was not until Louis XIV took the throne that the biggest transformations of the port began; he pulled down the city walls in 1666 and expanded the port to the Rive Neuve (New Riverbank). The city was devastated by plague in 1720, losing more than half its population. By the time of the Revolution, Marseille was on the rebound once again, with industries of soap manufacturing and oil processing flourishing, encouraging a wave of immigration from Provence and Italy. With the opening of the Suez Canal in 1869, Marseille became the greatest boomtown in 19th-century Europe. With a large influx of immigrants from areas as exotic as Tangiers, the city quickly acquired the multicultural population it maintains to this day.

The infinite variety of street life, the nooks and crannies of the medieval Barri Gòtic, the ceramic tile and stained glass of Art Nouveau facades, the art and music, the throb of street life, the food (ah, the food!)—one way or another, Barcelona will find a way to get your full attention. The capital of Catalonia is a banquet for the senses, with its beguiling mix of ancient and modern architecture, tempting cafés and markets, and sun-drenched Mediterranean beaches. A stroll along La Rambla and through waterfront Barceloneta, as well as a tour of Gaudí's majestic Sagrada Famíliaand his other unique creations, are part of a visit to Spain's second-largest city. Modern art museums and chic shops call for attention, too. Barcelona's vibe stays lively well into the night, when you can linger over regional wine and cuisine at buzzing tapas bars.

Believed to be the oldest town on the Iberian Peninsula, the Andalusian port of Cádiz enjoys a stunning location at the edge of a six-mile promontory. The town itself, with 3,000 years of history, is characterised by pretty white houses with balconies often adorned with colourful flowers. As you wander around be sure to take a stroll through the sizeable Plaza de Espãna, with its large monument dedicated to the first Spanish constitution, which was signed here in 1812. Cádiz has two pleasant seafront promenades which boast fine views of the Atlantic Ocean, and has a lovely park, the Parque Genoves, located close to the sea with an open-air theatre and attractive palm garden. Also notable is the neo-Classical cathedral, capped by a golden dome.

Lying near the head of Southampton Water, a peninsula between the estuaries of the Rivers Test and Itchen, Southampton is Britain’s largest cruise port. It has been one of England’s major ports since the Middle Ages, when it exported wool and hides from the hinterland and imported wine from Bordeaux. The city suffered heavy damage during World War Two and as a result the centre has been extensively rebuilt, but there are still some interesting medieval buildings including the Bargate, one of the finest city gatehouses in England.